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Summary
Award-winning, clinically formulated serum hydrates, smooths, and firms while supporting the skin barrier. Powered by hyaluronic acid filling spheres, a gentle retinol alternative, and antioxidants to improve elasticity, texture, tone, and resilience.
Benefits
- Firm + Hydrate + Smooth + Brighten
- Formulated by Facial Plastic Surgeon, Dr. Paul Nassif
- "Originally created to prepare my patients’ skin before surgery—and help it recover faster afterward. Today, it’s a daily essential that floods the skin with hydration and visibly restores firmness, smoothness, and glow—like resetting skin to its healthiest state.”
Features
- Our best-selling serum takes a 360 approach to fast, visible anti-aging results and truly healthier skin. You’ll notice deep hydration, bounciness, brighter tone, smoother texture, and youthful resilience
- Delivers powerful antioxidants to halt skin cell damage and brighten skin tone
- Helps to promote collagen production for elasticity, firmness, and wrinkle reduction
- Optimizes skin’s natural moisture production from the deepest layers
- Clinically Proven via Corneometer and Cutometer to Improve Hydration, the appearance of Firmness, Texture, Fine Lines and Wrinkles Crepey Skin
- A clear golden serum with a luxuriously silky feel that absorbs quickly and leaves skin smooth, soft, and comforted—no tackiness. The scent is subtle and pleasant
Key Ingredients
- Hyaluronic Filling Spheres™ - A dehydrated form of Hyaluronic Acid that swells with moisture when applied. Helps provide intense moisturization, improve the look of deeper lines and wrinkles, improve skin firmness and elasticity, and add volume to the appearance of facial contours
- Ceramide NP - A naturally-occurring component of the skin’s outer layers, it supports the renewal of the skin's natural protective layer and forms an effective barrier against moisture loss
- Retinol - Commonly known as vitamin A, retinol is a skin-restoring, wrinkle-smoothing, firming ingredient and an antioxidant that can improve a range of visible signs of aging
- Sytenol® A - A natural antioxidant and skin-restoring ingredient found in the babchi plant. Its soothing and smoothing properties help reduce the look of fine lines and wrinkles, boost collagen production, improve skin texture, and even the skin tone
- Retinol Molecular Film Fluid - A very thin film with stabilized retinol and vitamin E to enhance delivery and absorption into the skin. Helps to minimize trans-epidermal water loss and provides a soft and pleasant feel to the skin
- Lipochroman® - A synthetic super potent antioxidant to help prevent damage to skin cells and tissues which trigger skin aging
Item 77006695
This ultra-versatile hybrid serum and moisturizer can be applied as a traditional serum after cleansing and toning and prior to your moisturizer; can be mixed into your moisturizer; or can be applied as the last step in your routine prior to applying makeup or sunscreen. Please allow it to dry down to a matte finish before applying your moisturizer, makeup or sunscreen. We recommend 1 pump in the morning and evening for optimal anti-aging benefits.
Cyclopentasiloxane, Cyclohexasiloxane, Dimethiconol, Dimethicone, Caprylyl Methicone, Ethylhexyl Palmitate, Ethylhexyl Cocoate, Retinol, Bakuchiol, Tetrahexyldecyl Ascorbate, Dimethylmethoxy Chromanol, Sodium Hyaluronate, Glycosphingolipids, Ceramide NP, Tocopherol, Glycine Soja (Soybean) Oil, Silica Dimethyl Silylate, Butylene Glycol, Pentylene Glycol, Tocopheryl Acetate, Parfum (Fragrance), Bisabolol, Tocotrienols, Elaeis Guineensis (Palm) Oil, Lecithin, Phenyl Trimethicone, Caprylyl Glycol, Squalene, Beta-Sitosterol, Octadecendioic Acid, Acetic Acid, Linalool, Geraniol, Amyl Cinnamal
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Reviews
Review Snapshot
by PowerReviews
Ratings Distribution
Most Helpful Positive Review
Love this product! My skin
Love this product! My skin drinks it in and it helps with facial lines. The few I have now. I use many of Dr. Nassif products but this one I will not be without, it's the best and I have used many other upscale brands. Will continue to purchase his products, at 72 my skin looks great.
Most Helpful Critical Review
CHANGE IT BACK TO THE "OLD" FORMULA AND BOTTLE
For years, I would rate this product 10 Stars! A non negotiable! I have literally raved over it so much that many of my friends have turned into loyal customers of NassifMD. I would never go without and anyone who says it's too greasy or that it doesn't do anything - is not using it when they're st...
449 results
A real MUST
Verified Buyer
Reviewed at

Comments about Hydro-Screen Serum
I can't say enough good things about this serum, 2 weeks in I can already see my results , some of my cheek wrinkles and crows feet are starting to soften and smoker lip lines have had the most dramatic results already. 77 yr old and to see these results this quickly is just amazing. Love this product can't wait to see results after longer useage
Love It
I love this oily serum with Vitamin C. I use Fresh Oil-infused serum then I use 1.5 pumps of this and liberally smear it across my face, neck, chest, and use any leftover on theback of my hands. If it is morning, I give it a few minutes to dry and top with Dr. G Sunscreen. The Nassif serum has made a big difference on my complexion and I saw real results in 2 days. Thanks Dr. Paul!
Best for neck and chest
Verified Buyer
Reviewed at

Comments about Hydro-Screen Serum
This is fabulous oil for neck and chest area. I use every day and have seen great improvement
Absolutely best skin product ever!!
Reviewed at

I use after my vit C and before my moisturizer. I honestly think this has made my skin look more hydrated and wrinkles are less defined. Over all I have dewy look to my skin making it more youthful. Im 60 and get compliments on my shin all the time, this product has definitely helped with that. I've used it for about 3 years now.
Horrible smell
This stuff is massively over perfumed with an overwhelming smell of roses. Really stinks!